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General Internal Medicine Clinical Trials

The following searchable list includes all the Division of General Internal Medicine - Department of Medicine clinical trials currently looking for participants. Please feel free to contact us with inquiries about any of our ongoing research.

Trials

Mediators of Atherosclerosis in South Asians Living in America

South Asian (Indian, Pakistani, Bangladeshi, Nepali, and Sri Lankan) individuals have high rates of cardiovascular disease that is not explained by traditional cardiovascular risk factors. Though South Asians represent over one-quarter of the world's population, there are no longitudinal studies in this high-risk ethnic group. The investigators aim to establish a longitudinal study of South Asians at two United States centers to identify risk factors linked to subclinical atherosclerosis and incident cardiovascular disease. The purpose of this study is to understand the causes of heart disease and stroke in South Asians and compare these causes to those in other United States ethnic groups.
Principal InvestigatorKandula, Namratha RKandula, Namratha R
ClinicalTrials.gov IdentifierNCT01207167IRB number STU00019837
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Low InTensity Exercise intervention in PAD: The LITE Trial.

This study is being done to determine whether an exercise intervention that avoids continuous supervision and exercise-related pain in the legs can improve walking ability in people with lower extremity peripheral artery disease (PAD).
Eligibility CriteriaPeripheral artery disease
Principal InvestigatorMcDermott, Mary McGraeMcDermott, Mary McGrae
Location(s)
  • Map it 201 E. Huron St.
    Chicago, IL
ClinicalTrials.gov IdentifierNCT02538900IRB number STU00105855
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Telmisartan Plus Exercise to Improve Functioning in PAD

The purpose of this study is to establish whether the angiotensin receptor blocker (ARB) telmisartan improves walking performance in people with PAD. We will also determine whether telmisartan plus supervised exercise improves walking performance more than telmisartan alone and more than supervised treadmill exercise alone. …
The purpose of this study is to establish whether the angiotensin receptor blocker (ARB) telmisartan improves walking performance in people with PAD. We will also determine whether telmisartan plus supervised exercise improves walking performance more than telmisartan alone and more than supervised treadmill exercise alone.
Eligibility CriteriaWe are asking you to take part in this research study because you have or may have peripheral artery disease (PAD). PAD is a condition in which cholesterol blockages in the leg arteries prevent blood from getting down to the legs and feet during exercise.
Principal InvestigatorMcDermott, Mary McGraeMcDermott, Mary McGrae
Location(s)
  • Map it 201 E. Huron St.
    Chicago, IL
ClinicalTrials.gov IdentifierNCT02593110IRB number STU00200954
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Improving Outpatient Safety of Older Adults through Electronic Patient Portals

The objective of this study is to assess whether providing caregivers of older adults proxy access to an electronic patient portal (MyChart) improves the outpatient medication safety and communication between caregivers and health care providers. …
The objective of this study is to assess whether providing caregivers of older adults proxy access to an electronic patient portal (MyChart) improves the outpatient medication safety and communication between caregivers and health care providers.
Eligibility CriteriaAdults age 65 and older, a patient in the General Internal Medicine and Geriatrics (NMFF GIM-GER) clinics, not currently enrolled in MyChart Electronic Patient Portal, English speaking, can identify a caregiver who assists with their care (can be informal e.g. adult child, spouse, caregiver agency). Additional eligibility criteria are focused on the caregiver identified: English speaking, assist the older adult with medications and communication with the health care team, and have internet access (either phone, tablet, or laptop/computer).
Principal InvestigatorLindquist, Lee ALindquist, Lee A
Location(s)
  • Map it 675 N. St. Clair St.
    Chicago, IL
IRB number STU00201242
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The ENabling Reduction of low-Grade Inflammation in SEniors) Pilot Study

The purpose of the ENRGISE Pilot Study is to look at the effect of anti-inflammatory drugs on physical functioning in older adults. This study will see if two study drugs (fish oil and losartan, a commonly used blood pressure medicine) have an effect on walking ability.…
The purpose of the ENRGISE Pilot Study is to look at the effect of anti-inflammatory drugs on physical functioning in older adults. This study will see if two study drugs (fish oil and losartan, a commonly used blood pressure medicine) have an effect on walking ability.
Eligibility CriteriaAge 70 or older, slow walking speed, and high levels of markers of inflammation in your blood.
Principal InvestigatorMcDermott, Mary McGraeMcDermott, Mary McGrae
Location(s)
  • Map it 201 E. Huron St.
    Chicago, IL
ClinicalTrials.gov IdentifierNCT02676466IRB number STU00201974
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Cocoa to Improve Walking Performance in Peripheral Artery Disease: The COCOA-PAD Study

The purpose of this study is to determine whether drinking daily cocoa-enriched beverages improves walking performance in people with PAD. Previous studies have shown that cocoa may improve blood flow, improve cardiovascular health, and improve muscle function and strength. Some evidence suggests that cocoa may also improve walking ability …
The purpose of this study is to determine whether drinking daily cocoa-enriched beverages improves walking performance in people with PAD. Previous studies have shown that cocoa may improve blood flow, improve cardiovascular health, and improve muscle function and strength. Some evidence suggests that cocoa may also improve walking ability in people with PAD.
Eligibility CriteriaWe are asking you to take part in this research study because you are age 65 or older and you have or may have peripheral artery disease (PAD). PAD is a condition in which cholesterol blockages in the leg arteries prevent adequate blood flow to the legs and feet.
Principal InvestigatorMcDermott, Mary McGraeMcDermott, Mary McGrae
Location(s)
  • Map it 201 E. Huron St.
    Chicago, IL
ClinicalTrials.gov IdentifierNCT02876887IRB number STU00202741
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